Tuterr, the Private Eye says:
"Yeah, kid? Still rambling on about an "interface"? God damn it... lemme put it straight with you, pal. You might want to go consult the Chief Medical Officer about your... condition. Maybe they will know something about your "key shortcuts" problem, whatever the hell that means."

This is a list of default keybindings and controls. You can rebind many of them with the Custom Keybindings menu in-game.

Humans and Other Carbon-based Lifeforms' Hotkeys

An old diagram of (most) human hotkeys.

Hotkey-mode Enabled

Hotkey-mode can be toggled on by pressing Tab. Many hotkeys can be reassigned through game preferences -> custom keybindings. This must be done on every server, as keybindings aren't shared between them.

W, A, S, D = Move your character
Q = Drop
E = Equip
R = Throw
B = Resist / Unbuckle yourself / Stop drop and roll when on fire /
T = Say (opens a new input window)
G = Give item to someone
Z/Y = Activate held object
X = Swap hands
4 or F = Toggle Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people.
O = OOC. Consider unbinding it if you fear accidentally saying IC(in character) things in OOC.
M = emote
H = Stop Pulling
U or click the rest button = Rest/lay down. You can crawl while laying down.
Shift + B = Put in hand item into backpack, or take out last item put into backpack.
Shift + E = Put in hand item into belt or belt slot, or take out last item put into belt.
Shift + Q = Put in hand item into suit storage slot, or take out last item put into suit storage slot.
Numpad 8, 4, 5, 6, 1, 2, 3 = Used for selecting body target. Numbers correspond to location on the target doll. 8 Cycles through Head -> Eyes -> Mouth

Any Mode

Arrow keys = Move your character.
Shift + Click = Examine something.
Shift + Doubleclick = Examine something closer.
Shift + Right click = Open context menu.
Shift + Middle Click = Point at something.
Alt + Click a tile = Open a new tab with a list of all the items of the clicked tile next to you.
Alt + Click a PDA = Remove the ID from the PDA.
Control + Click a PDA = Take out pen.
Control + Shift + Click a PDA = Take out cartridge.
Alt + Click a locker = Lock the locker.
Alt + Click a clothing = Toggles any possible aesthetic settings (breath mask up/down, rolling down jumpsuit, buttons labcoat, flip baseball cap etc).
Alt + Click a bag/container = Opens the container. Also works on things that are in another container.
Alt + Click a microwave = Turns the microwave on.
Alt + Click a chem dispenser, chemical heater, ChemMaster 3000 or PanD.E.M.I:C = Ejects any loaded beaker.
Alt + Click a vent or scrubber while having a "ventcrawl" ability = Crawl into the pipes. Monkeys, slimes and several other creatures can do this.
Control + Up/Down = In your text bar will shift through the history of everything you've entered in the red bar at the bottom.
Control + Click = Pull an object or person you're standing next to.
While pulling something, click an empty floor tile with empty hand = Drag the pulled object to the clicked floortile if possible.
End = Toggle throwing mode.
Page Down = Use the object in your active hand.
Middle Mouse Button or Page Up = Switch your active hand.
Click the Drop button on your HUD = Drop the item in your active hand.
Delete = Stop pulling.
F12 = Toggle minimal HUD.
Spacebar = While entering commands in red bar auto-completes them.
Tab = Toggle between hotkey and normal mode. While in hotkey mode, WASD will move your character.
Esc = Stops you from being stuck moving in one direction (due to lag or other issues).

Other Humanoid Controls

These are actions you can perform which require other methods than hotkeys.

Ordinary right-click. It doesn't matter if Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people. is on or not. your jumpsuit = Change suit sensor mode.
Click-drag a person to yourself = Opens the other person's inventory, where you can remove or add worn objects and also turn their internals on or off.
Open someone's inventory while you are prone next to them = Lets you untie their shoelaces.
Click-drag yourself to a table = Attempt to climb the table.
Click table while someone else is attempting to climb it = Push them away.
Click-drag a bag/container onto another bag/container = Attempts to move all contents of the first bag to the other.
Hold CTRL and left-click a person with your hand empty. It doesn't matter if Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people. is on or off. Repeat after a short delay to upgrade grab to aggressive (lvl 2), neck (lvl 3) and strangling (lvl 4). a prone person aggressively and then drag them to yourself (your sprite) = Fireman carry them.
Have someone else Hold CTRL and left-click a person with your hand empty. It doesn't matter if Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people. is on or off. Repeat after a short delay to upgrade grab to aggressive (lvl 2), neck (lvl 3) and strangling (lvl 4). you aggressively, and then you click and drag your own sprite to them = Piggyback ride them.
Click a table while fireman carrying person = Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people. off: Place gently , or Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people. on: Slam their targeted bodypart on the table.
Hold CTRL and left-click a person with your hand empty. It doesn't matter if Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people. is on or off. Repeat after a short delay to upgrade grab to aggressive (lvl 2), neck (lvl 3) and strangling (lvl 4). yourself while aiming for bleeding limb = Grasp your bodypart to slightly reduce blood flow. Must be done with your other arm if one is the one bleeding.
Hold CTRL and left-click a person with your hand empty. It doesn't matter if Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people. is on or off. Repeat after a short delay to upgrade grab to aggressive (lvl 2), neck (lvl 3) and strangling (lvl 4). a small animal and then click-drag the animal to yourself = Scoop up the animal. Doesn't work on all animals.

Hotkeys for the AI

Double-Click a tile = Instantly jump there.
Double-Click people = Start tracking the person.
Ctrl + number key (0-9) = Saves your current camera location.
Number key (0-9) = Jumps camera to saved camera location. Tilde and zero will return you to the last spot you jumped from.

Hotkeys for the AI and Cyborgs

Shift + Click a door = Open/close.
Control + Click a door = Bolts down/up.
Control + Shift + Click a door = Emergency access on/off.
Alt + Click a door = Electrify on/off.
Control + Click an APC = Power on/off.
Control + Click a Turret Control = Power on/off.
Alt + Click a Turret Control = Lethal/stun mode.

Cyborg Hotkey-mode Enabled

Cyborgs have many of the basic hotkeys and controls that humans have. You need to not have a module active to be able to open lockers, unbuckle people from chairs and such with your left clicks. But you do not have hands so you can not pick up most things.

Cyborg specific hotkeys:

X = Cycle active modules
1 = Activate first module
2 = Activate second module
3 = Activate third module

Other Cyborg Controls

Click-drag humanoid to self with Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people. on = Opens the interact window of the target (undress window).
Click-drag humanoid to self with Combat Mode Enable with 4, disable with 1 or toggle with F by default. Left-clicking people with an empty hand will Harm them if on, or Help them if off. Prevents you from switching places or being pushed when colliding with people. off = Buckles target to self.
Click yourself without active module (or resist) = Unbuckles person from self.
Use *spin emote with someone buckled to you = Forcefully throws the buckled person forward, which stuns them (even if they didn't hit anything).

Keyboard Shortcuts

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