How would you design it?
Me? I'd have it be part sim city manager and part dwarf fortress. You'd start with a basic city weighed you're tasked with expanding by adding on additional departments, allocating resources, and managing the station's budget. You'd also bee able to hire new crew members with different strengths, weaknesses, and needs. You'd have to keep them happy though by making sure their needs are filled our they might just go postal and start murdering their co-workers.
There'd be a papers, please element to it as well in that you'd have to do background checks on new employees unless you want to risk syndicate scum sneaking onto the station. If your detectives can't track them down fast enough bad things start to happen. Crew members start turning up dead. Money and resources start disappearing, bombs start going off, singularities start getting released, and eldritch abominations start popping up.