Bottom post of the previous page:
Harpsichord has anti-synergy with Echo Chamber as it is not an agenda that can be stolen, it is an asset that gives you 1 agenda point under specific conditions.These cards aren't as powerful as they seem, and I am struggling to imagine a deck that can make serious use of them. Unlike the runner, the corp already has plenty of ways to burn a turn of setup for an agenda point, and they were always seen as really low value and bad because 1 agenda point scores from the corp's perspective rarely help because you need to generally burn at least 4 turns (2 per agenda) to get enough agenda points for the points to be relevant. 1 pointers were almost always run for their effect as a result, with their status as agendas being secondary or used for combos in Weyland. Even though these cards can't be stolen they still increase the ratio of cards that need defending to cards that defend other cards and that is a struggle.
Echo chamber is, essentially, a 1/3 point agenda that has the effect "can't be stolen, doesn't cost credits to advance." While self protection is nice it isn't likely good enough to overcome the problems 1/3s have.
Gene Splicer seems even weirder, because it has anti-synergy with pretty much every Jinteki deck that would want to run it. First, its important to remember it is a very weak trap, with it dealing 2 damage rather than 4 on a turn it fires. It also can't ever realistically instakill a runner as when advanced far enough a runner would likely either assume its a junebug, do something like driveby it, or would just let you take the 1 agenda point if they think it is splicing. Gene splicing is a 1/4 that costs 1 extra credit to score, and which deals 2 net damage if its and can't be stolen, only trashed. Remember that low amounts of net damage are a minor tax, not really a threat, once the runner has their rig up. Feedback Filter also exists and turns net damage into a 3 credit tax, and it isn't an uncommon card.
The really interesting thing about this isn't the fact it deals damage, but that its a trash cost to deny you points, but IG doesn't need 1 pointers at all as their agenda choices make the value of them questionable unless you can multiscore. Harmony just flat out doesn't have the money to use this effect. Palana doesn't have time for this bullshit. Biotech doesn't have any real meaningful interaction with this card save maybe really weird interactions with The Tank.
This makes PE slightly more taxing and trap dense (but PE doesn't need more trap density, and note this is NOT you scoring an agenda, its added as if it was an agenda, same deal as Mad Dash not hurting the runner extra hard if "scored" playing against PE, and because PE already taxes on 1/3 theft it seems better to just run 1/3s with good score effects) but seems to ACTUALLY matter the most in RP decks (As any access on a pseudo-agenda is painful and RP decks benefit from a "dead" turn to set up a 1 point score if it ever gets accessed) and Tennin Institute (they can score this without actions and make use of their corporate ability on turns they can't protect agendas, giving it more similar value to a 2/1 than a 4/1). However I think the most realistic home for this card is Potential Unleashed, which is more likely than any other ID to not have a "Solved" agenda distribution and dramatically benefits from any time something a runner has to do costs net.
Its important to be really cognizant of how little value a 1 agenda point card has on its own. Mad Dash requires a lone click of setup and is supported by cards any Shaper is going to use anyway, and still doesn't see universal play despite being a free runner controlled agenda point. Corps already control their own agenda points, already score them based on windows when the runner can't run, and already have the option for 1/3s. I think the fact the runner can't get the 1/3 isn't going to overcome the fact most of these are textless or pseudo textless.
The big exception may be Weyland because having more agendas to sacrifice is always good, and because many of their agendas are run as "Triple Operations" they often end up with agenda schemes where getting a random 1 pointer out dramatically changes the game state. Also it makes archer MUCH easier to Rez "legitimately" early game. When I read Echo Chamber as "NBN, 1/3 agenda that must be advanced in one turn and can't be stolen, only trashed" I am not as intimidated as when I read "Weyland, 1/3, must be advanced as a pesudo-triple operation, get a free rez of Archer." Archer being on a scoring server early game is seriously scary shit and in a Weyland deck can easily end the game fast.